Pfizer Expects Lung Cancer Drug Lorbrena to Hit Over $1 Billion in Sales After Exceptional 5-Year Data

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Pfizer has announced that its lung cancer drug, Lorbrena, is projected to generate over $1 billion in annual sales by 2030, driven by positive clinical trial results.

Pfizer Anticipates $1 Billion Annual Sales of Lorbrena

According to Reuters, data released on Friday revealed that a majority of patients with a rare form of advanced lung cancer in a clinical trial had no disease progression for five years and were still alive after treatment with Lorbrena.

Lorbrena targets a specific gene mutation called anaplastic lymphoma kinase (ALK), similar to Pfizer's earlier drug, Xalkori.

Results from the company's Phase 3 CROWN trial revealed at the Chicago's American Society of Clinical Oncology annual meeting showed that 60% of ALK-positive patients treated with Lorbrena experienced no disease progression after five years, a stark contrast to the 8% for those treated with Xalkori.

Additionally, 53% of Lorbrena patients with brain metastases were disease-free after five years.

Pfizer Expects Lung Cancer Drug Lorbrena to Hit Over $1 Billion in Sales After Exceptional 5-Year Data
Pfizer has announced that its cancer drug, Lorbrena, is projected to generate over $1 billion in annual sales by 2030. ANGELA WEISS/AFP via Getty Images

Sales of Lobrena Surge

Since its US approval in March 2021, Lorbrena's sales have surged, reaching $164 million in the first quarter of 2024, a 46% increase from the previous year.

Pfizer anticipates continued double-digit growth for the drug, which is vital to its strategy to offset declining COVID-19 vaccine sales and refocus on its oncology portfolio.

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