Moderna Inc. has secured a boost in its efforts against avian influenza, with the US government awarding the pharmaceutical giant $176 million to accelerate the development of its bird flu vaccine, Reuters reported.
The urgency of this initiative stems from the alarming spread of the H5N1 virus, which has now affected over 130 dairy herds across 12 states since its initial detection earlier this year. VCPost has learned that bird flu has already been detected in Minnesota for the first time, and more US states might be on the list soon.
Scientists fear prolonged exposure to the virus in poultry and dairy farming environments could facilitate mutations that increase its transmissibility among humans, posing a pandemic risk.
Moderna Bird Flu Vaccine
Based in Cambridge, Massachusetts, Moderna aims to use these funds from the US Biomedical Advanced Research and Development Authority to advance late-stage development and testing of an mRNA-based vaccine explicitly designed for H5N1 avian influenza.
This investment will improve the country's preparedness against potential public health threats, with additional provisions for rapid response capabilities in case of future outbreaks.
Moderna's mRNA-1018 vaccine, currently undergoing safety and immunogenicity studies among adults aged 18 and older, targets both the circulating H5 subtype observed in dairy cattle and the H7 bird flu subtype.
The results from these ongoing studies, expected later this year, will guide the final stages of vaccine development and regulatory approval processes.
While preparations are underway to potentially distribute 4.8 million doses of the vaccine to protect farm workers and other high-risk populations, health officials maintain that the general public faces a low current risk from bird flu.
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